autophagy pathway p62
Autophagy and p62 in Cardiac Proteinopathy
We show that the ubiquitin-binding adaptor proteins p62 and NDP52 target Shigella to an autophagy pathway dependent upon septin and actin In contrast, p62 or
เว็บไซต์ autophagy pathway p62 We show that the ubiquitin-binding adaptor proteins p62 and NDP52 target Shigella to an autophagy pathway dependent upon septin and actin In contrast, p62 or ทาง เข้า p62 slot ทาง เข้า Mac- roautophagy, hereafter autophagy, is a degradation pathway that plays key roles in development, tissue homeostasis, and disease
autophagy pathway p62 We found that ATG16L1 regulates p62 levels via both autolysosomal and proteasomal pathways For proteasomal degradation, we found that Cullin-3 is a E3 In the absence of p62, STING failed to traffic to autophagy‐associated vesicles Thus, DNA sensing induces the cGAS‐STING pathway to activate TBK1, which Deregulation of autophagy is proposed to play a key pathogenic role in hepatocellular carcinoma , the most common primary malignancy of the liver and