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p62   Consequently, p62 is degraded following an increase in autophagic flux for which this protein cur- rently serves as an indicator However, the This review focuses on the role of p62 in linking the ubiquitin–proteasome system and autophagy pathway upon ubiquitinated protein degradation

p62 overexpression resulted in a progressive and robust pathology model with neuronal inclusions and neurodegeneration p62 gene transfer could be a novel Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

The p62 protein remains associated with the nuclear pore complex-lamina fraction p62 is synthesized as a soluble cytoplasmic precursor of 61 kDa followed by View our 7 p62SQSTM1 products for your research including p62SQSTM1 Primary Antibodies and p62SQSTM1 Small Molecules